EL HUSSEINY’S Essentials Of Endocrinology For USMLE Step 1 pdf

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EL HUSSEINY’S Essentials Of Endocrinology

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EL HUSSEINYS ESSENTIALS OF ENDOCRINOLOGY.pdf – 19.0 MB

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Table of Contents 

Endocrinology – Embryology
 Pharyngeal apparatus 1
 Thyroid Gland Embryology 4
 Digeorge Syndrome 5
Endocrinology – Anatomy and Pathophysiology
 Hypothalamic – Anterior Pituitary System 7
 Pituitary Gland 8
 Growth Hormone 10
 Gigantism 12
 Acromegaly 12
 Pituitary Dwarfism 13
 Pituitary Infantilism 14
 Prolactin 14
 Pituitary Tumors 15
 Sheehan’s Syndrome 17
 Pituitary Apoplexy 17
 Posterior Pituitary 19
 Antidiuretic Hormone (vasopressin) 19
 Diabetes Insipidus 21
 Primary (Psychogenic) Polydipsia 23
 Syndrome of inappropriate antidiuretic hormone secretion (SIADH) 24
 Oxytocin 26
 Adrenal Gland 27
 Biosynthetic pathways of steroid hormone synthesis 29
 Physiological effect of cortisol (glucocorticoid) 31
 Physiologic action of aldosterone 34
 Juxtaglomerular Apparatus 35
 Physiologic action of androgens and estrogens 37
 Cushing syndrome 38
 Adrenal insufciency 42
 Adrenal crisis 44
 Primary hyperaldosteronism (Conn’s syndrome) 45
 Secondry hyperaldosteronism 46
 Congenital adrenal hyperplesia 47

Adrenal medulla 51
 Pheochromocytoma 52
 Neuroblastoma 53
 Thyroid gland 53
 Physiologic action of thyroid hormones 57
 Hypothyroidism 58
 Hyperthyroidism 61
 Thyroid cancer 64
 Calcium hemostasis 66
 Parathyroid hormone 66
 Calcitonin 68
 Vitamin D (cholecalciferol) 68
 Hypercalcemia 71
 Hypocalcemia 73
 Vitamin D deficiency 74
 Pancreas 76
 Insulin 76
 Glucose transport 77
 Physiologic action of insulin 79
 Control of insulin secretion 80
 Physiologic action of glucagon 83
 Control of glucagon secretion 84
 Diabetes mellitus 84
 Complication of diabetes mellitus 89
 Pancreatic endocrine-secreting tumors 95
 Multiple endocrine neoplasias 98
 Signaling pathways of endocrine hormones 99
Endocrinology – Pharmacology
 Diabetes mellitus drugs 105
 Insulin preperations 105
 Oral hypoglycemic drugs 107
 Propylthiouracil, methimazole 112
 Other antithyroid medications 112
 Levothyroxine (T4), triiodothyronine (T3) 114
 Hypothalamic/pituitary drugs 114
 Demeclocycline 114
 Glucocorticoids 114
 Cinacalcet 115